| Also known as: |
Myelin Basic Protein / MBP |
| Other names: |
Golli-MBP, Myelin A1 protein, Myelin basic protein, Myelin membrane encephalitogenic protein, myelin A1 protein, myelin basic protein, myelin basic protein, myelin membrane encephalitogenic protein, myelin basic protein isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MBP |
| Other gene names: |
MBP, MBP, N/A, MBP |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
12 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Chicken, Due to limited knowledge and inability for testing each and every species, Guinea pig, Human (Homo sapiens), Mammal, Mouse (Mus musculus), Pig, Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Sheep, the reactivity of the antibody may extend to other species which are not listed hereby, Bovine |
| Specificity and cross-reactivity: |
Clone 12 has been reported as being suitable for use in Western blotting, Further epitope analysis indicates binding to a region defined by amino acids 82-87 (DENPVV), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Synthetic peptide Reacts very well, The Reacts weakly with peptides ending in the Phe 91 where the 91-92 Phe-Phe bond is broken, This particular antibody might cross react with speacies outside of the listed ones, as does intact MBP, Reacts with myelin basic protein from a wide range of species |
| Form/Appearance: |
0, 0, 1% sodium azide, 1M Tris, Tissue culture supernatant |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Radioimmunoassay (RIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Description: |
7 are often produced recombinant and shouldn&rsquo, Basic proteins pH>, t be precipitated by formic acid buffer |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Latin name: |
Rattus norvegicus |
| Gene target: |
Monoclonal [ 12] (IgG2a) Myelin Protein / MBP |
| Short name: |
Monoclonal [clone 12] (IgG2a) Myelin Protein / MBP Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Host: |
Rat |
| Isotype: |
IgG2a |
| Species: |
Bos Taurus genes are available form the Bovine Genome database, Rats, Bovine |
| Alternative name: |
Rat monoclonal [clonality 12] (IgG2a) to Bovine Myelin Basic Protein / MBP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6925 |
| Gene: |
MBP |
More about : MBP |
| Long gene name: |
myelin basic protein |
| Locus: |
18q23 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
4155 |
| Pubmed identfication: |
2425357 |
| RefSeq identity: |
NM_001025081 |
| Havana BLAST/BLAT: |
OTTHUMG00000132874 |