| Also known as: |
SERPINA1 / Alpha 1 Antitrypsin |
| Other names: |
Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Alpha-1-antitrypsin, SPAAT, Serpin A1Short peptide from AAT, alpha-1 protease inhibitor, alpha-1-antiproteinase, alpha-1-antitrypsin, alpha-1-antitrypsin, alpha-1-antitrypsin null, antitrypsin), clade A, clade A (alpha-1 antiproteinase, member 1, member 1, protease inhibitor 1 (anti-elastase), serine (or cysteine) proteinase inhibitor, serpin A1, serpin peptidase inhibitor, alpha-1-antitrypsin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SERPINA1 |
| Other gene names: |
A1A, A1AT, AAT, AAT, PI, PI, PI1, PRO2275, SERPINA1, SPAAT, alpha1AT, SERPINA1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
No cross-reactivity with alpha-1-acid glycoprotein, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, serum albumin or other serum proteins, Recognizes human alpha-1-Antitrypsin |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
0, pH 7, 1% sodium azide, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Immunohistochemistry (IHC - Paraffin) |
| Description: |
- or alpha protein sometimes glycoprotein present in blood, The Mouse Monoclonal (IgG2a) SERPINA1 / Alpha 1 Antitrypsin Antibody is a &alpha |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal (IgG2a) SERPINA1 / Alpha 1 Antitrypsin |
| Short name: |
Mouse Monoclonal (IgG2a) SERPINA1 / Alpha 1 Antitrypsin Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
antitrypsin), clade A (a-1 antiproteinase, member 1 / a 1 Antitrypsin (Antibody to), sapiens serpin peptidase inhibitor, Mouse monoclonal (IgG2a) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
A1A and A1AT and AAT and alpha1AT and PI and PI1 and PRO2275, Extracellular, SERPINA1 and IDBG-18174 and ENSG00000197249 and 5265, SERPINA1 and IDBG-634001 and ENSBTAG00000018843 and 280699, Serpina1f and IDBG-167371 and ENSMUSG00000021081 and 68348, antitrypsin), clade A (alpha-1 antiproteinase, identical protein binding, member 1, this GO :0001948 and glycoprotein binding and molecular function this GO :0002020 and protease binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006953 and acute-phase response and biological process this GO :0007596 and blood coagulation and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0030162 and regulation of proteolysis and biological process this GO :0030168 and platelet activation and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0002020 : protease binding and also this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding, this GO :0002020 : protease binding, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, serpin peptidase inhibitor |
| Identity: |
8941 |
| Gene: |
SERPINA1 |
More about : SERPINA1 |
| Long gene name: |
serpin family A member 1 |
| Synonyms gene: |
PI |
| Synonyms gene name: |
antitrypsin), antitrypsin), clade A (alpha-1 antiproteinase, clade A (alpha-1 antiproteinase, member 1 , member 1 serpin peptidase inhibitor, serine (or cysteine) proteinase inhibitor |
| Synonyms: |
AAT A1A PI1 alpha-1-antitrypsin A1AT alpha1AT |
| Synonyms name: |
alpha-1-antitrypsin , protease inhibitor 1 (anti-elastase) |
| Locus: |
14q32, 13 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X01683 |
| Entrez gene record: |
5265 |
| Pubmed identfication: |
24172014 |
| RefSeq identity: |
NM_001002235 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000150355 |