| Also known as: |
CD22 |
| Other names: |
B-cell receptor CD22, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, B-lymphocyte cell adhesion molecule, BL-CAM, BL-CAM, CD22 antigen, CD22 molecule, Sialic acid-binding Ig-like lectin 2, Siglec-2, T-cell surface antigen Leu-14, T-cell surface antigen Leu-14, sialic acid binding Ig-like lectin 2, sialic acid-binding Ig-like lectin 2, B-cell receptor CD22 isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD22 |
| Other gene names: |
BL-CAM, CD22, SIGLEC-2, SIGLEC2, SIGLEC2, Siglec-2, CD22 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
Bu59 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD22 expression is lost upon terminal differentiation to plasma cells, CD22 functions as an adhesion receptor, CD22 is expressed in the cytoplasm of pro-B and pre-B cells and then on the cell surface of mature B cells, Initially, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD22 is differentially expressed during B cell maturation, a 130/140kD cell surface glycoprotein which is expressed by cells of B-lymphocyte lineage, and a signalling molecule which may play a role in B-cell activation, for leucocytes and erythrocytes, CD22 Recognises human CD22 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD22 |
| Short name: |
MOUSE Anti-HUMAN CD22 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD22 molecule (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD22 and IDBG-44001 and ENSG00000012124 and 933, CD22 and IDBG-635610 and ENSBTAG00000011887 and 514582, Cd22 and IDBG-171574 and ENSMUSG00000030577 and 12483, Cell surfaces, SIGLEC-2 and SIGLEC2, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding, CD22 molecule |
| Identity: |
1643 |
| Gene: |
CD22 |
More about : CD22 |
| Long gene name: |
CD22 molecule |
| Synonyms gene name: |
CD22 antigen |
| Synonyms: |
SIGLEC-2 SIGLEC2 |
| Synonyms name: |
sialic acid binding Ig-like lectin 2 |
| Locus: |
19q13, 12 |
| Discovery year: |
1991-06-06 |
| GenBank acession: |
X52785 |
| Entrez gene record: |
933 |
| Pubmed identfication: |
8496602 1691828 |
| RefSeq identity: |
NM_001771 |
| Classification: |
C2-set domain containing CD molecules Sialic acid binding Ig like lectins |
| Havana BLAST/BLAT: |
OTTHUMG00000183298 |