| Also known as: |
CD301 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD301 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
ER-MP23 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas, Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, Expression of CD301 is induced by alternative (i, IL-4/IL-13 mediated) activation of macrophages and dendritic cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antibody binds both MGL1 and MGL2 homologues, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone ER-MP23 is reported to block the function of mouse CD301, _x000D__x000D_In mice, a 38 kD cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR), but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated, which are probably recent immigrants from peripheral connective tissue sites, CD301 Recognises murine CD301, e |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunofluorescence (IF), Immunohistology - Frozen (IHC), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD301 |
| Short name: |
RAT ANTI MOUSE CD301 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD301 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16916 |
| Gene: |
CLEC10A |
More about : CLEC10A |
| Long gene name: |
C-type lectin domain family 10 member A |
| Synonyms gene: |
CLECSF13 CLECSF14 |
| Synonyms gene name: |
C-type (calcium dependent, carbohydrate-recognition domain) lectin, member A , superfamily member 14 (macrophage-derived) C-type lectin domain family 10 |
| Synonyms: |
HML2 HML CD301 |
| Synonyms name: |
macrophage lectin 2 (calcium dependent) |
| Locus: |
17p13, 1 |
| Discovery year: |
2003-08-06 |
| GenBank acession: |
D50532 |
| Entrez gene record: |
10462 |
| Pubmed identfication: |
8598452 |
| RefSeq identity: |
NM_006344 |
| Classification: |
CD molecules C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000177939 |