| Also known as: |
CD11a |
| Other names: |
CD11 antigen-like family member A, CD11 antigen-like family member A, Integrin alpha-L, LFA-1A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, Lymphocyte antigen 15, alpha L integrin, alpha polypeptide, integrin alpha L, integrin alpha-L, leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, lymphocyte antigen 15, lymphocyte function associated antigen 1, Integrin alpha-L |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD11a |
| Other gene names: |
(p180), Cd11a, Itgal, LFA-1, LFA-1A, LFA-1A, Lfa-1, Ly-15, Ly-15, Ly-15, Ly-21, Itgal |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
I21/7 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD11a is a member of the intergrin family of adhesion molecules, Clone I21/7 is reported to block the cytolytic activity of cytotoxic T cell lines, ICAM-1, ICAM-2 and ICAM-3 and is involved in cell-cell adhesion processes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The CD11a molecule is expressed on all leucocytes and associates with CD18 to form a heterodimer at the cell surface, The CD11a/CD18 heterodimer binds to intercellular adhesion molecules (ICAM), This particular antibody might cross react with speacies outside of the listed ones, a 170 - 180kD type I membrane glycoprotein, which is also known as the integrin alphaL subunit, CD11a This item recognises murine CD11a |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunoprecipitation (IP) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD11a |
| Short name: |
RAT ANTI MOUSE CD11a Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD11a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6148 |
| Gene: |
ITGAL |
More about : ITGAL |
| Long gene name: |
integrin subunit alpha L |
| Synonyms gene: |
CD11A |
| Synonyms gene name: |
alpha L (antigen CD11A (p180), alpha polypeptide) , integrin, lymphocyte function-associated antigen 1 |
| Synonyms: |
LFA-1 |
| Synonyms name: |
alpha polypeptide , antigen CD11A (p180) lymphocyte function-associated antigen 1 |
| Locus: |
16p11, 2 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
3683 |
| Pubmed identfication: |
3284962 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000176964 |