| Long name: |
Noxa Primary Polyclonal Antibody |
| Also known as: |
Noxa PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Noxa |
| Specificity: |
This is a highly specific antibody against Noxa |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Noxa |
| Gene ID number: |
5366 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity), Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1, Contributes to p53/TP53-dependent apoptosis after radiation exposure, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria, Promotes proteasomal degradation of MCL1, Promotes activation of caspases and apoptosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APR, APR_HUMAN, Immediate early response protein APR, Immediate-early-response protein APR, PMA induced protein 1, PMA-induced protein 1, PMAIP1, Phorbol 12 myristate 13 acetate induced protein 1, Phorbol-12-myristate-13-acetate-induced protein 1, Protein Noxa, Adult T cell leukemia derived PMA responsive |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Noxa |
| Short name: |
Noxa Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Noxa (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9108 |
| Gene: |
PMAIP1 |
More about : PMAIP1 |
| Long gene name: |
phorbol-12-myristate-13-acetate-induced protein 1 |
| Synonyms: |
APR NOXA |
| Locus: |
18q21, 32 |
| Discovery year: |
1991-08-12 |
| GenBank acession: |
D90070 |
| Entrez gene record: |
5366 |
| Pubmed identfication: |
2398525 12879012 |
| RefSeq identity: |
NM_021127 |
| Classification: |
BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT: |
OTTHUMG00000132765 |