| Long name: |
Recombinant Human Inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB) |
| Alternative names: |
I-kappa-B kinase 2, I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK-B, IKK2, Inhibitor of nuclear factor kappa-B kinase subunit beta, NFKBIKB, Nuclear factor NF-kappa-B inhibitor kinase beta, inhibitor of kappa light polypeptide gene enhancer in B-cells, inhibitor of nuclear factor kappa-B kinase subunit beta, kinase beta, nuclear factor NF-kappa-B inhibitor kinase beta, inhibitor of nuclear factor kappa-B kinase subunit beta isoform 2 |
| Gene name: |
IKBKB |
| Other gene names: |
I-kappa-B-kinase beta, IKBKB, IKK-B, IKK-beta, IKK-beta, IKK2, IKK2, IKKB, IKKB, IMD15, IkBKB, NFKBIKB, NFKBIKB, IKBKB |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Inhibitor of nuclear factor kappa-B kinase subunit beta(IKBKB) is a recombinant protein expressed in Mammalian Cell |
| Product category: |
Recombinant Proteins |
| Expression system: |
Mammalian Cell |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Description: |
Complex subunit associated factors are involved in hybridoma growth, Eosinohils, NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells, Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , Tissue, activator, caspase, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Aplha, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
Inhibitor of factor kappa-B kinase subunit beta (IKBKB) |
| Short name: |
Inhibitor of factor kappa-B kinase subunit beta (IKBKB) |
| Species: |
Humans, Human |
| Alternative name: |
kinase b), sapiens suppressor on nuclear factor kappa-B phosphorylation catalyst functionnal sequence b (inhibitor on kappa light polypeptide gene enhancer in B-cells, H |
| Alternative to gene target: |
DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0097110 and scaffold protein binding and molecular function this GO :2001259 and positive regulation of cation channel activity and biological process, IKBKB and IDBG-19987 and ENSG00000104365 and 3551, IKBKB and IDBG-629838 and ENSBTAG00000007599 and 281854, IKK-beta and IKK2 and IKKB and IMD15 and NFKBIKB, Ikbkb and IDBG-141021 and ENSMUSG00000031537 and 16150, alcohol group as acceptor, alcohol group as acceptor and also this GO :0019901 : protein kinase binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity and also this GO :0097110 : scaffold protein binding, alcohol group as acceptor and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, kinase beta, leucine rich repeat containing receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042501 and serine phosphorylation of STAT protein and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045893 and positive regulation of transcription, nuclei, this GO :0001782 and B cell homeostasis and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006954 and inflammatory response and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008384 and IkappaB kinase activity and molecular function this GO :0008385 and IkappaB kinase complex and cellular component this GO :0009103 and lipopolysaccharide biosynthetic process and biological process this GO :0009615 and response to virus and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0010765 and positive regulation of sodium ion transport and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008384 : IkappaB kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008384 : IkappaB kinase activity, this GO :0016772 : transferase activity, this GO :0016773 : phosphotransferase activity, this GO :0019901 : protein kinase binding, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, this GO :0097110 : scaffold protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773 : phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, inhibitor of kappa light polypeptide gene enhancer in B-cells |
| Identity: |
5960 |
| Gene: |
IKBKB |
More about : IKBKB |
| Long gene name: |
inhibitor of nuclear factor kappa B kinase subunit beta |
| Synonyms gene name: |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| Synonyms: |
IKK2 NFKBIKB IKK-beta IKKB |
| Locus: |
8p11, 21 |
| Discovery year: |
1998-02-11 |
| GenBank acession: |
AF029684 |
| Entrez gene record: |
3551 |
| Pubmed identfication: |
9878263 9763654 18308615 |
| Havana BLAST/BLAT: |
OTTHUMG00000164092 |