| Long name: |
ALEXA FLUOR 647 Conjugated, KiSS1 receptor Polyclonal Antibody |
| Also known as: |
Anti-KiSS1 receptor PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KiSS1 receptor |
| Specificity: |
This is a highly specific antibody against KiSS1 receptor |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
139-157/398 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KiSS1 receptor |
| Gene ID Number: |
84634 |
| Swiss Prot: |
Q969F8 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins, KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity, The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood, The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells, The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself, The receptor is essential for normal gonadotropin-released hormone physiology and for puberty, a C-terminally amidated peptide of KiSS1, Receptor for metastin (kisspeptin-54 or kp-54) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
HOT7T175 AXOR12 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the KiSS1 receptor Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
KiSS1 receptor |
| Short name: |
KiSS1 receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, KiSS1 receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4510 |
| Gene: |
KISS1R |
More about : KISS1R |
| Long gene name: |
KISS1 receptor |
| Synonyms gene: |
GPR54 |
| Synonyms gene name: |
G protein-coupled receptor 54 |
| Locus: |
19p13, 3 |
| Discovery year: |
1999-03-12 |
| GenBank acession: |
AB051065 |
| Entrez gene record: |
84634 |
| Pubmed identfication: |
10100623 |
| RefSeq identity: |
NM_032551 |
| Classification: |
Peptide receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000181900 |