| Long name: |
TANK Primary Polyclonal Antibody |
| Also known as: |
TANK PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TANK |
| Specificity: |
This is a highly specific antibody against TANK |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TANK |
| Gene ID number: |
10010 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
For example, Specifically, TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, and inhibit LMP1-mediated NF kappa B activation, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB, or TRAF3, the Epstein Barr virus transforming protein, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm, this protein can block TRAF2 binding to LMP1, TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
I-TRAF, ITRAF, TANK_HUMAN, TRAF family member associated NF KAPPA B activator, TRAF family member associated NFKB activator, TRAF family member-associated NF-kappa-B activator, TRAF interacting protein, TRAF interacting protein TANK isoform a, TRAF interacting protein TANK isoform b, TRAF-interacting protein, TRAF2, Tank, I TRAF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TANK |
| Short name: |
TANK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TANK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11562 |
| Gene: |
TANK |
More about : TANK |
| Long gene name: |
TRAF family member associated NFKB activator |
| Synonyms gene: |
TRAF2 |
| Synonyms gene name: |
TRAF family member-associated NFKB activator |
| Synonyms: |
I-TRAF |
| Locus: |
2q24, 2 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
U59863 |
| Entrez gene record: |
10010 |
| Pubmed identfication: |
8710854 8855313 |
| RefSeq identity: |
NM_133484 |
| Havana BLAST/BLAT: |
OTTHUMG00000132037 |