| Long name: |
ALEXA FLUOR 488 Conjugated, GPR17 Polyclonal Antibody |
| Also known as: |
Anti-GPR17 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPR17 |
| Specificity: |
This is a highly specific antibody against GPR17 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human G protein coupled receptor 17 |
| Gene ID Number: |
2840 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
GPR17, GPR17, GPR17 is thought to play a role in mediating neuronal death, In some neurons, Two named isoforms of GPR17 exist as a result of alternative splicing events, Upon brain injury, While GPR17 is expressed in kidney, a membrane receptor for uracil nucleotide and CysLTs, also known as uracil nucleotide/cysteinyl leukotriene receptor or P2Y-like receptor (P2YL), heart and umbilical vein endothelial cells, increase significantly at the site of damage, infiltrating the lesioned area, is a 367 amino acid member of the G-protein coupled receptor 1 family of proteins, is upregulated as well, it is expressed in the highest levels in the brain, remodeling brain circuitries by microglia and initiating remyelination in damaged neurons, the extracellular concentrations of nucleotides and cysteinyl leukotrienes (CysLTs), two families of endogenous signaling molecules, G protein-coupled receptor 17 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GPR17 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GPR17 |
| Short name: |
GPR17 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, G protein-coupled receptor 17 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GPR17 and IDBG-639124 and ENSBTAG00000006261 and 782442, GPR17 and IDBG-69246 and ENSG00000144230 and 2840, Gpr17 and IDBG-133208 and ENSMUSG00000052229 and 574402, Plasma membranes, chemokine receptor activity, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity, this GO :0004950 : chemokine receptor activity, G protein-coupled receptor 17 |
| Identity: |
4471 |
| Gene: |
GPR17 |
More about : GPR17 |
| Long gene name: |
G protein-coupled receptor 17 |
| Locus: |
2q14, 3 |
| Discovery year: |
1995-11-21 |
| Entrez gene record: |
2840 |
| Pubmed identfication: |
8558062 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000131533 |