| Long name: |
ALEXA FLUOR 488 Conjugated, FUT7/FucT-VII Polyclonal Antibody |
| Also known as: |
Anti-FUT7/FucT-VII PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FUT7/FucT-VII |
| Specificity: |
This is a highly specific antibody against FUT7/FucT-VII |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FUT7/FucT-VII |
| Gene ID Number: |
2529 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Alpha 1, Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules, Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, determine cell surface-carbohydrate profiles, such as the fucosyltransferases, which are reliant on adhesion molecules such as Selectins (1-3), which is an essential interface for biological recognition processes, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6), 3-fucosyltransferase VII (FucT-VII) mediates the targeting of effector T cells to sites of inflammation by modifying surface ligands which are compatible to endothelial selectins (7), Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FUT7/FucT-VII Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
FUT7/FucT-VII |
| Short name: |
FUT7/FucT-VII Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, FUT7/FucT-VII (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4018 |
| Gene: |
FUT7 |
More about : FUT7 |
| Long gene name: |
fucosyltransferase 7 |
| Synonyms gene name: |
fucosyltransferase 7 (alpha (1, 3) fucosyltransferase) |
| Synonyms name: |
alpha (1, 3) fucosyltransferase |
| Locus: |
9q34, 3 |
| Discovery year: |
1994-12-14 |
| GenBank acession: |
X78031 AB012668 |
| Entrez gene record: |
2529 |
| Pubmed identfication: |
8207002 8182079 |
| RefSeq identity: |
NM_004479 |
| Classification: |
Fucosyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000020964 |
| Locus Specific Databases: |
Blood Group Antigen Mutation Database |