| Long name: |
Biotin Conjugated, FAU/MNSF-beta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FAU/MNSF-beta |
| Specificity: |
This is a highly specific antibody against FAU/MNSF-beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human FAU/MNSF-beta |
| Gene ID number: |
2197 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A wide range of enzymes facilitate in the proteolytic Ub pathway, MNSF-beta is a ubiquitin-like fusion protein consisting of the ribosomal protein S30 and a protein that shares 36% sequence identity with ubiquitin, The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex, The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate, The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component, This ubiquitin-like segment (Ubi-L) can be cleaved from MNSF-beta in the cytosol, a subunit of MNSF, including monoclonal nonspecific suppressor factor-beta (MNSF-beta), which is a lymphokine product of a murine T cell hybrid-oma that restricts the production of LPS-induced immunoglobulin secreting cells in an antigen-nonspecific manner, The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
RPS30 FLJ22986 Fub1 Fubi MNSFbeta asr1 S30 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FAU/MNSF-beta Conjugated |
| Short name: |
Conjugated, FAU/MNSF-beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, FAU/MNSF-b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3597 |
| Gene: |
FAU |
More about : FAU |
| Long gene name: |
FAU, ubiquitin like and ribosomal protein S30 fusion |
| Synonyms gene name: |
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived) Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed |
| Synonyms name: |
ribosomal protein S30 Monoclonal nonspecific suppressor factor beta |
| Locus: |
11q13, 1 |
| Discovery year: |
1992-12-02 |
| GenBank acession: |
AK026639 |
| Entrez gene record: |
2197 |
| Pubmed identfication: |
8406491 |
| RefSeq identity: |
NM_001997 |
| Classification: |
S ribosomal proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000165606 |