| Long name: |
Biotin Conjugated, Dymeclin Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Dymeclin |
| Specificity: |
This is a highly specific antibody against Dymeclin |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Dymeclin |
| Gene ID number: |
54808 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Cutaneous cells of affected individuals show dilated rough endoplasmic reticulum and enlarged vacuoles, Defects in dymeclin are also the cause of Smith-McCort dysplasis syndrome (SMC), It is a widely expressed multi-pass membrane protein, The Dyggve-Melchior-Clausen syndrome protein, a rare autosomal recessive disorder, also designated dymeclin, detected primarily in chondrocytes and fetal brain tissue, is characterized by microcephaly, may play a role in proteoglycan metabolism and intracellular protein digestion, short trunk dwarfism and sometime psychomotor retardation, which has characteristics identical to those of Dyggve-Melchior-Clausen syndrome, Dyggve-Melchior-Clausen syndrome (DMC) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
DYM, DYM_HUMAN, Dyggve-Melchior-Clausen syndrome protein, FLJ20071, FLJ90130, SMC, DMC |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Dymeclin Conjugated |
| Short name: |
Conjugated, Dymeclin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Dymeclin (Antibody to) |
| Alternative technique: |
antibodies |