| Long name: |
Cy3 Conjugated, DMC1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DMC1 |
| Specificity: |
This is a highly specific antibody against DMC1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DMC1 |
| Gene ID number: |
11144 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Additional proteins involved in the pathway include Nibrin and Dmc1, An alternative spliced form of Dmc1, Dmc1 is specifically involved in meiotic recombination, Nibrin, Overexpression of Rad52 confers resistance to ionizing radiation and induces homologous intrachromosomal recombination, Rad51 is essential for mitotic and meiotic recombination, Rad52 is thought to be involved in an early stage of Rad51-mediated recombination, The DNA repair proteins Rad51 and Rad52 are key components of the double-strand-break repair (DSBR) pathway, The alternatively spliced Dmc1-D transcript is detected in both male and female germ cells, and its mutation in yeast and mammalian cells results in chromosome loss, designated Dmc1-D, indicating that the encoded protein may have a role in mammalian genetic recombination in meiosis, is absent in Nijemegen breakage syndrome (NBS) patients, is deleted for a region between the two motifs involved in nucleotide binding, which complexes with Mre11 and Rad50, DNA repair proteins are necessary for the maintenance of chromosome integrity and are involved in the elimination of premutagenic lesions from DNA |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
LIM15 |
| Properties: |
1 of the DMC1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DMC1 Conjugated |
| Short name: |
Conjugated, DMC1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, DMC1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2927 |
| Gene: |
DMC1 |
More about : DMC1 |
| Long gene name: |
DNA meiotic recombinase 1 |
| Synonyms gene name: |
DMC1 (dosage suppressor of mck1, meiosis-specific homologous recombination (yeast) , yeast homolog) meiosis-specific homologous recombination DMC1 dosage suppressor of mck1 homolog |
| Locus: |
22q13, 1 |
| Discovery year: |
1999-10-29 |
| GenBank acession: |
D63882 |
| Entrez gene record: |
11144 |
| Pubmed identfication: |
8602360 8590282 17541404 |
| RefSeq identity: |
NM_007068 |
| Havana BLAST/BLAT: |
OTTHUMG00000151088 |