| Catalog number: | bs-12997R-A594 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | Destrin Antibody, ALEXA FLUOR 594 |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | ALEXA FLUOR 594 Conjugated, Destrin Polyclonal Antibody |
|---|---|
| Also known as: | Anti-Destrin PAb ALEXA FLUOR 594 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 594, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Destrin |
| Specificity: | This is a highly specific antibody against Destrin |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Destrin |
| Gene ID Number: | 11034 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | ADF and Cofilin are Actin-depolymerizing proteins whose activities are possibly regulated by their phosphorylation/dephosphorylation, ADF depolymerizes F-Actin by interacting directly with F-Actin protomers, ADF shares 71% sequence homology with Cofilin, As a result of different cleavage sites on ADF and Cofilin, Sensitivity to polyphosphoinositides may be a common feature in vitro among Actin-binding proteins such as ADF and Cofilin that can bind to G-Actin and regulate the state of Actin polymerization, The Actin-depolymerizing activity of ADF is reversibly controlled by changes in KCl concentration but is insensitive to calcium concentration, The difference in the function of ADF and Cofilin results from the subtle difference in their amino acid sequence rather than possible differences in posttranslational modifications, also known as destrin, however the two proteins differ in their interaction with Actin, is a member of the ADF/Cofilin/destrin superfamily that has the ability to rapidly depolymerize F-Actin in a stoichiometric manner, the proteins differ in their overall tertiary folds, Actin-depolymerizing factor (ADF) |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 590nm/617nm |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: | Alexa conjugate 1 |
| Gene target: | Destrin |
| Short name: | Destrin Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 594 |
| Alternative name: | ALEXA FLUOR 594, Destrin (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 44548 |
| Gene: | DSTNP4 | More about : DSTNP4 |
| Long gene name: | actin depolymerizing factor pseudogene 4 , destrin |
| Synonyms gene name: | destrin (actin depolymerizing factor) pseudogene 4 |
| Locus: | 3p22, 2 |
| Discovery year: | 2012-11-15 |
| Entrez gene record: | 729454 |
| Havana BLAST/BLAT: | OTTHUMG00000156247 |
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