| Long name: |
Cy5, 5 Conjugated, CRTAP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CRTAP |
| Specificity: |
This is a highly specific antibody against CRTAP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CRTAP |
| Gene ID number: |
10491 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, CRTAP is widely expressed with predominant expression in articular chondrocytes, In the endoplasmic reticulum (ER), It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation, Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B, OI, OI type 7 is a mild form of this disorder, also known as brittle bone disease, extracellular fibril assembly and intracellular trafficking, is characterized by bone fragility and susceptibility to fractures, the major structural proteins of skin and bone, while OI type 2B is a neonatal lethal condition, CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
CASP LEPREL3 P3H5 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
CRTAP Conjugated |
| Short name: |
Conjugated, CRTAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, CRTAP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2379 |
| Gene: |
CRTAP |
More about : CRTAP |
| Long gene name: |
cartilage associated protein |
| Synonyms name: |
leprecan-like 3 prolyl 3-hydroxylase family member 5 (non-enzymatic) |
| Locus: |
3p22, 3 |
| Discovery year: |
1999-10-19 |
| GenBank acession: |
AJ006470 |
| Entrez gene record: |
10491 |
| Pubmed identfication: |
9217321 10429950 |
| Havana BLAST/BLAT: |
OTTHUMG00000130746 |
| Locus Specific Databases: |
Osteogenesis Imperfecta Variant Database LRG_4 |