| Long name: |
Cy5, 5 Conjugated, GABA B Receptor 2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GABA B Receptor 2 |
| Specificity: |
This is a highly specific antibody against GABA B Receptor 2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
573-597/971 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human GABA B Receptor 2 |
| Gene ID number: |
9568 |
| Swiss Prot: |
O75899 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, Plays a critical role in the fine-tuning of inhibitory synaptic transmission, Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, Signaling inhibits adenylate cyclase, Within the heterodimeric GABA receptor, activates potassium channels, formed by GABBR1 and GABBR2, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis, muscle relaxation and antinociception, only GABBR1 seems to bind agonists, slow wave sleep, stimulates phospholipase A2, such as adenylate cyclase, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials, while GABBR2 mediates coupling to G proteins, Component of a heterodimeric G-protein coupled receptor for GABA |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
G-protein coupled receptor 51, GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, GABBR2, GPR51, GPRC3B, Gamma-aminobutyric acid type B receptor subunit 2, Gb2, HRIHFB2099, HG20 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
GABA B Receptor 2 Conjugated |
| Short name: |
Conjugated, GABA B Receptor 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, GABA B Receptor 2 (Antibody to) |
| Alternative technique: |
antibodies |