| Long name: |
ALEXA FLUOR 594 Conjugated, GREM2 Polyclonal Antibody |
| Also known as: |
Anti-GREM2 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GREM2 |
| Specificity: |
This is a highly specific antibody against GREM2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GREM2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Additionally, All family members are secreted proteins that act as BMP antagonists in embryonic explants and are expressed in the proximal airway epithelium of the lung during embryonic development, Gremlin-1 is required for early limb outgrowth and patterning in the FGF4-SHH feedback loop, The dorsaling factor gremlin belongs to a novel gene family that includes the head-inducing factor Cerberus and the tumor suppressor DAN, secreted gremlin relays the sonic hedgehog signal from the polarizing region to the apical ectodermal ridge, while gremlin-2 binds and blocks the activity of BMP-2 and BMP-4, The gremlin protein family contains antagonists of bone morphogenetic protein (BMP) signaling that are expressed in the neural crest |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Prdc FLJ21195 CKTSF1B2 DAND3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
GREM2 |
| Short name: |
GREM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, gremlin 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, GREM2 and IDBG-107671 and ENSG00000180875 and 64388, Grem2 and IDBG-206362 and ENSMUSG00000050069 and 23893, protein homodimerization activity, this GO :0005125 and cytokine activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0008201 and heparin binding and molecular function this GO :0010172 and embryonic body morphogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0036122 and BMP binding and molecular function this GO :0038098 and sequestering of BMP from receptor via BMP binding and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0048263 and determination of dorsal identity and biological process this GO :0060300 and regulation of cytokine activity and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0008201 : heparin binding and also this GO :0036122 : BMP binding and also this GO :0042803 : protein homodimerization activity, this GO :0008201 : heparin binding, this GO :0036122 : BMP binding, this GO :0042803 : protein homodimerization activity, gremlin 2 |
| Identity: |
17655 |
| Gene: |
GREM2 |
More about : GREM2 |
| Long gene name: |
DAN family BMP antagonist , gremlin 2 |
| Synonyms gene name: |
cysteine knot superfamily, gremlin 2, homolog (Xenopus laevis) gremlin 2 |
| Synonyms name: |
protein related to DAN and cerberus |
| Locus: |
1q43 |
| Discovery year: |
2004-07-30 |
| GenBank acession: |
AK024848 |
| Entrez gene record: |
64388 |
| Pubmed identfication: |
15039429 |
| RefSeq identity: |
NM_022469 |
| Classification: |
DAN family |
| Havana BLAST/BLAT: |
OTTHUMG00000039909 |