| Long name: |
ARFBP1 Primary Polyclonal Antibody |
| Also known as: |
ARFBP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ARFBP1 |
| Specificity: |
This is a highly specific antibody against ARFBP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARF6 |
| Gene ID number: |
382 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
'Lys-61' and 'Lys-81', Also ubiquitinates the p53/TP53 tumor suppressor and core histones including H1, Binds to an upstream initiator-like sequence in the preprodynorphin gene, H2A, H2B, H3 and H4, May regulate abundance of CDC6 after DNA damage by polyubiquitinating and targeting CDC6 to degradation, Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41', Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1, Regulates neural differentiation and proliferation by catalyzing the polyubiquitination and degradation of MYCN, thereby playing a role in base-excision repair, E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ARF BP1, ARF-BP1, ARF-binding protein 1, BJ-HCC-24 tumor antigen, E3 ubiquitin protein ligase HUWE1, E3 ubiquitin-protein ligase HUWE1, HECT, HECT UBA and WWE domain containing protein 1, HECT domain protein LASU1, HUWE, HUWE1_HUMAN, HectH9, Homologous to E6AP carboxyl terminus homologous protein 9, Huwe1, Ib772, KIAA0312, KIAA1578, LASU1, Large structure of UREB1, MULE, Mcl 1 ubiquitin ligase E3, Mcl-1 ubiquitin ligase E3, UBA and WWE domain-containing protein 1, URE B1, URE-B1, URE-binding protein 1, UREB 1, UREB1, Upstream regulatory element-binding protein 1, ARF binding protein 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ARFBP1 |
| Short name: |
ARFBP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ARFBP1 (Antibody to) |
| Alternative technique: |
antibodies |