| Long name: |
Cy5, 5 Conjugated, DD1/AKR1C1/DD2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DD1/AKR1C1/DD2 |
| Specificity: |
This is a highly specific antibody against DD1/AKR1C1/DD2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DD1 |
| Gene ID number: |
1645 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AKR1C3 and 3alpha-HSD are alternate designations for human DD3 (which is referred to as AKR1C18 in rodents), BABP or DDH2, CD, CHDR or AKR1C6 (in rodents), DD1 and DD2 are 20alpha-HSDs, DD1 and DD2 are ubiquitously expressed, DD3 is a unique enzyme that can specifically catalyze the dehydrogenation of trans-benzenedihydrodiol and trans-naphthalenedihydrodiol, DDH or DDH1, NADPH-dependent oxidoreductase that reduces 3-keto-5-dihydrosteroids to their tetrahydro products, The 20alpha-HSD catalyzes the reaction of progesterone to the inactive form 20alpha-hydroxyprogesterone, The 3alpha-HSD is a cytosolic, The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor, dDD, monomeric, pesticides and steroid hormones, such as polycyclic aromatic hydrocarbons, whereas DD3 and DD4 are the 3alpha-HSDs, whereas DD4 mRNA is restricted to the liver, while DD2 also can be designated AKR1C2, while DD4 also can be called AKR1C4, DD1 is also designated AKR1C1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
DD BABP DD2 HAKRD MCDR2 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
DD1/AKR1C1/DD2 Conjugated |
| Short name: |
Conjugated, DD1/AKR1C1/DD2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, DD1/AKR1C1/DD2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
385 |
| Gene: |
AKR1C2 |
More about : AKR1C2 |
| Long gene name: |
aldo-keto reductase family 1 member C2 |
| Synonyms gene: |
DDH2 TDD |
| Synonyms gene name: |
3-alpha hydroxysteroid dehydrogenase, aldo-keto reductase family 1, bile acid binding protein, member C2 (dihydrodiol dehydrogenase 2, type III) testicular 17, 20-desmolase deficiency |
| Synonyms name: |
3-alpha hydroxysteroid dehydrogenase, bile acid binding protein, dihydrodiol dehydrogenase 2, type III |
| Locus: |
10p15, 1 |
| Discovery year: |
1994-09-14 |
| GenBank acession: |
L32592 |
| Entrez gene record: |
1646 |
| Pubmed identfication: |
9716498 21802064 |
| RefSeq identity: |
NM_001354 |
| Classification: |
Aldo-keto reductases |
| Havana BLAST/BLAT: |
OTTHUMG00000017584 |