| Long name: |
ALEXA FLUOR 647 Conjugated, DD1/AKR1C1/DD2 Polyclonal Antibody |
| Also known as: |
Anti-DD1/AKR1C1/DD2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DD1/AKR1C1/DD2 |
| Specificity: |
This is a highly specific antibody against DD1/AKR1C1/DD2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DD1 |
| Gene ID Number: |
1645 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
AKR1C3 and 3alpha-HSD are alternate designations for human DD3 (which is referred to as AKR1C18 in rodents), BABP or DDH2, CD, CHDR or AKR1C6 (in rodents), DD1 and DD2 are 20alpha-HSDs, DD1 and DD2 are ubiquitously expressed, DD3 is a unique enzyme that can specifically catalyze the dehydrogenation of trans-benzenedihydrodiol and trans-naphthalenedihydrodiol, DDH or DDH1, NADPH-dependent oxidoreductase that reduces 3-keto-5-dihydrosteroids to their tetrahydro products, The 20alpha-HSD catalyzes the reaction of progesterone to the inactive form 20alpha-hydroxyprogesterone, The 3alpha-HSD is a cytosolic, The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor, dDD, monomeric, pesticides and steroid hormones, such as polycyclic aromatic hydrocarbons, whereas DD3 and DD4 are the 3alpha-HSDs, whereas DD4 mRNA is restricted to the liver, while DD2 also can be designated AKR1C2, while DD4 also can be called AKR1C4, DD1 is also designated AKR1C1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
DD BABP DD2 HAKRD MCDR2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the DD1/AKR1C1/DD2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
DD1/AKR1C1/DD2 |
| Short name: |
DD1/AKR1C1/DD2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, DD1/AKR1C1/DD2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
385 |
| Gene: |
AKR1C2 |
More about : AKR1C2 |
| Long gene name: |
aldo-keto reductase family 1 member C2 |
| Synonyms gene: |
DDH2 TDD |
| Synonyms gene name: |
3-alpha hydroxysteroid dehydrogenase, aldo-keto reductase family 1, bile acid binding protein, member C2 (dihydrodiol dehydrogenase 2, type III) testicular 17, 20-desmolase deficiency |
| Synonyms name: |
3-alpha hydroxysteroid dehydrogenase, bile acid binding protein, dihydrodiol dehydrogenase 2, type III |
| Locus: |
10p15, 1 |
| Discovery year: |
1994-09-14 |
| GenBank acession: |
L32592 |
| Entrez gene record: |
1646 |
| Pubmed identfication: |
9716498 21802064 |
| RefSeq identity: |
NM_001354 |
| Classification: |
Aldo-keto reductases |
| Havana BLAST/BLAT: |
OTTHUMG00000017584 |