| Catalog number: | bs-12391R-Cy7 |
|---|---|
| Price: | 525 € |
| Supplier: | MBS Polyclonals |
| Product name: | Mib1/Mindbomb Antibody, Cy7 Conjugated |
| Quantity: | 100ug |
| Related search: |
| Long name: | Cy7 Conjugated, Mib1/Mindbomb Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy7 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Mib1/Mindbomb |
| Specificity: | This is a highly specific antibody against Mib1/Mindbomb |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human Mib1/Mindbomb |
| Gene ID number: | 57534 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Although it seems to be widely expressed at low levels, Both DAPK and MIB1 are overexpressed in epileptic brain tissue, Delta, MIB1 also interacts with DAPK, MIB1 is expressed at highest concentrations in the CNS and ovary, MIB1 ubiquinates Delta by binding to its intracellular domain, Ubiquination of DAPK leads to inhibition of caspase-dependent apoptosis, a protein that plays an important role in the regulation of apoptosis, leading to the endocytosis and eventual degradation of the Delta receptor, paradoxically, results in the up-regulation of receptor activity and enhances Notch signaling, suggesting that they probably cooperate as regulators of neuronal death in epilepsy, therefore it is likely that overexpression of MIB1 can lead to tumor growth, which, MIB1 is a 1006 amino acid E3 ubiquitin ligase that activates the Notch ligand |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 743nm/767nm |
| Synonyms: | DIP-1, Dip 1, Dip1, E3 ubiquitin protein ligase MIB 1, E3 ubiquitin protein ligase MIB1, E3 ubiquitin-protein ligase mib1, MIB1_HUMAN, Mind bomb homolog 1, Zinc finger ZZ type with ankyrin repeat domain protein 2, mib1, DAPK-interacting protein 1 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: | Mib1/Mindbomb Conjugated |
| Short name: | Conjugated, Mib1/Mindbomb Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy7 |
| Alternative name: | cyanine 7 coupled, mindbomb E3 ubiquitin protein ligase 1/Mindbomb (Antibody to) |
| Alternative technique: | antibodies |
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