| Long name: |
FITC Conjugated, GABRG3/GABA A Receptor gamma 3 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GABRG3/GABA A Receptor gamma 3 |
| Specificity: |
This is a highly specific antibody against GABRG3/GABA A Receptor gamma 3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GABRG3/GABA A Receptor gamma 3 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
-2, Both GABAA and GABAC are ligand-gated ion channels, GABA T-2 and GABA T-3 (also designated GAT-1, GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC, GABA transporters have also been identified and include GABA T-1, GABAA R Beta 1-3, GABAA R Delta, GABAA R Epsilon, GABAA R Gamma 1-3, GABAA R Zeta 1 and GABAA R Zeta 2, In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing, Members of the GABAA receptor family include GABAA R Alpha 1-6, The GABA transporters function to terminate GABA action, The GABAB family is composed of GABAB R1 Alpha and GABAB R1 Beta, and -3), function to catalyze the production of GABA (gamma-aminobutyric acid), glutamate decarboxylases, however, they are structurally and functionally distinct, GAD-65 and GAD-67 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GABRG3/GABA A Receptor gamma 3 Conjugated |
| Short name: |
FITC Conjugated, GABRG3/GABA A Receptor gamma 3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GABRG3/GABA A Receptor g 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4088 |
| Gene: |
GABRG3 |
More about : GABRG3 |
| Long gene name: |
gamma-aminobutyric acid type A receptor gamma3 subunit |
| Synonyms gene name: |
gamma 3 , gamma-aminobutyric acid (GABA) A receptor |
| Synonyms name: |
GABA(G) receptor, gamma 3 |
| Locus: |
15q12 |
| Discovery year: |
1994-07-15 |
| Entrez gene record: |
2567 |
| Pubmed identfication: |
7601451 |
| Classification: |
Gamma-aminobutyric acid type A receptor subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000044462 |