| Long name: |
FITC Conjugated, GPRC5B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPRC5B |
| Specificity: |
This is a highly specific antibody against GPRC5B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human G protein coupled receptor family C group 1 member B |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
G protein-coupled receptors (GPCRs or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins, GPRC5B is an orphan receptor member of the G protein-coupled receptor 3 family, GPRC5B is highly expressed in kidney, Key roles for G protein-coupled receptors include control of protein maturation and cell surface delivery, This retinoic acid-inducible G protein-coupled receptor provides evidence for a possible interaction between retinoid and G protein signaling pathways, and has moderate expression in brain, and providing the correct framework for interactions with both heterotrimeric G proteins and arrestins to allow signal generation and termination, heart, pancreas and testis, prostate, retinoic acid-induced gene 2 protein) is a 403 amino acid protein encoded by the human GPRC5B gene, small intestine and spleen, GPRC5B (G protein-coupled receptor family C group 5 member B |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
RAIG-2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPRC5B Conjugated |
| Short name: |
FITC Conjugated, GPRC5B Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GPRC5B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13308 |
| Gene: |
GPRC5B |
More about : GPRC5B |
| Long gene name: |
G protein-coupled receptor class C group 5 member B |
| Synonyms gene name: |
G protein-coupled receptor, class C, family C, family C, group 1, group 5, group 5, member B , member B G protein-coupled receptor, member B G protein-coupled receptor |
| Locus: |
16p12, 3 |
| Discovery year: |
2000-01-11 |
| GenBank acession: |
AF202640 |
| Entrez gene record: |
51704 |
| Pubmed identfication: |
10493829 10783259 |
| Classification: |
Class C orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000131460 |