| Long name: |
HRP Conjugated, ², 4 Antibody, CACNB4/L-type Ca++ CPÎ |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
², 4, CACNB4/L-type Ca++ CPÎ |
| Specificity: |
², 4, This is a highly specific antibody against CACNB4/L-type Ca++ CPÎ |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
², 4, KLH conjugated synthetic peptide derived from human CACNB4/L-type Ca++ CPÎ |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CACNLB4 or CAB4, Functioning as one of the four components of the Beta subunit, L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an Alpha1 subunit, L-type Ca++ CP Beta 4, L-type Ca++ CP Beta 4 increases the peak calcium current in voltage-dependent calcium channels, The Beta subunit is encoded by four genes, Two isoforms of L-type Ca++ CP Beta4 exist due to alternative splicing events, a Beta subunit, a Beta subunit and an Alpha2 Gamma subunit, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the Beta subunit, also known as CACNB4 (Calcium channel voltage-dependent subunit beta 4), brain and smooth muscle, designated Beta1-Beta 4, is a 484 amino acid protein that contains one SH3 domain and is expressed in ovary, thereby shifting the voltage dependencies of activation and inactivation and controlling G protein inhibition and Beta membrane targeting, Voltage-dependent calcium channels are essential for the release of neurotransmitters |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
EJM4 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
², 4 Conjugated, CACNB4/L Ca++ CPÎ |
| Short name: |
Conjugated, ², 4 Antibody, CACNB4/L-type Ca++ CPÎ |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
b 4 subunit/L-classification Ca+and CPÎ, horseradish peroxidase coupled, voltage-dependent, ², 4 (Antibody to), calcium channel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CAB4 and CACNLB4 and EA5 and EIG9 and EJM and EJM4 and EJM6, CACNB4 and IDBG-641796 and ENSBTAG00000002297 and 282161, CACNB4 and IDBG-72371 and ENSG00000182389 and 785, Cacnb4 and IDBG-170902 and ENSMUSG00000017412 and 12298, Plasma membranes, beta 4 subunit, glutamatergic and biological process this GO :0042391 and regulation of membrane potential and biological process this GO :0045202 and synapse and cellular component this GO :0046058 and cAMP metabolic process and biological process this GO :0048536 and spleen development and biological process this GO :0048538 and thymus development and biological process this GO :0048541 and Peyer's patch development and biological process this GO :0048747 and muscle fiber development and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050877 and neurological system process and biological process this GO :0050908 and detection of light stimulus involved in visual perception and biological process this GO :0051899 and membrane depolarization and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :1901385 and regulation of voltage-gated calcium channel activity and biological process, protein kinase binding, this GO :0005245 and voltage-gated calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005891 and voltage-gated calcium channel complex and cellular component this GO :0006810 and transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0007214 and gamma-aminobutyric acid signaling pathway and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007411 and axon guidance and biological process this GO :0007528 and neuromuscular junction development and biological process this GO :0007628 and adult walking behavior and biological process this GO :0008331 and high voltage-gated calcium channel activity and molecular function this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0014051 and gamma-aminobutyric acid secretion and biological process this GO :0019227 and neuronal action potential propagation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0035249 and synaptic transmission, this GO :0005245 : voltage-gated calcium channel activity, this GO :0005245 : voltage-gated calcium channel activity and also this GO :0005515 : protein binding and also this GO :0008331 : high voltage-gated calcium channel activity and also this GO :0019901 : protein kinase binding, this GO :0005515 : protein binding, this GO :0008331 : high voltage-gated calcium channel activity, this GO :0019901 : protein kinase binding, voltage-dependent, calcium channel |
| Identity: |
1404 |
| Gene: |
CACNB4 |
More about : CACNB4 |
| Long gene name: |
calcium voltage-gated channel auxiliary subunit beta 4 |
| Synonyms gene name: |
beta 4 subunit , calcium channel, voltage-dependent |
| Locus: |
2q23, 3 |
| Discovery year: |
1997-04-21 |
| GenBank acession: |
AF038852 |
| Entrez gene record: |
785 |
| Pubmed identfication: |
9628818 |
| RefSeq identity: |
NM_000726, 3 |
| Classification: |
Calcium voltage-gated channel subunits Membrane associated guanylate kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000155091 |