| Long name: |
NFIA/NF-1 Primary Polyclonal Antibody |
| Also known as: |
NFIA/NF-1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NFIA/NF-1 |
| Specificity: |
This is a highly specific antibody against NFIA/NF-1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NFIA/NF-1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene, GRP 78, HSP 70, Histone H1, NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes, alpha-globin, also designated CTF, and activates transcription through a putatively novel, carboxy terminal transactivation domain, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription, including that of Ha-Ras, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter, proline-rich, NF-1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CCAAT Box Binding Transcription Factor, CCAAT-box-binding transcription factor, CTF, FLJ39164, NF I/A, NF-I/A, NF1 A, NF1-A, NF1A, NFI A, NFI L, NFI-A, NFIA, NFIA_HUMAN, Nuclear Factor 1 A, Nuclear Factor 1A, Nuclear Factor I A, Nuclear Factor IA, Nuclear factor 1 A type, Nuclear factor 1 A-type, Nuclear factor 1/A, Nuclear factor I/A, Nuclear factor I/X, TGGCA binding protein, TGGCA-binding protein, nuclear factor I/X CCAAT-binding transcription factor, ynuclear factor I/X CCAAT-binding transcription factor, CCAAT binding transcription factor |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NFIA/NF-1 |
| Short name: |
NFIA/NF-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NFIA/NF-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7784 |
| Gene: |
NFIA |
More about : NFIA |
| Long gene name: |
nuclear factor I A |
| Synonyms gene name: |
nuclear factor I/A |
| Synonyms: |
NFI-L KIAA1439 |
| Locus: |
1p31, 3 |
| Discovery year: |
1995-03-09 |
| GenBank acession: |
U07809 |
| Entrez gene record: |
4774 |
| Pubmed identfication: |
7590749 |
| RefSeq identity: |
NM_005595 |
| Havana BLAST/BLAT: |
OTTHUMG00000008618 |