| Long name: |
ALEXA FLUOR 350 Conjugated, TRAF3 Polyclonal Antibody |
| Also known as: |
Anti-TRAF3 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRAF3 |
| Specificity: |
This is a highly specific antibody against TRAF3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
130-180/568 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRAF3 |
| Gene ID Number: |
7187 |
| Swiss Prot: |
Q13114 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Down-regulates proteolytic processing of NFKB2, Inhibits TRAF2-mediated activation of NF-kappa-B, Inhibits activation of NF-kappa-B in response to LTBR stimulation, Is an essential constituent of several E3 ubiquitin-protein ligase complexes, May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins, Part of signaling pathways leading to the production of cytokines and interferon, Plays a role T-cell dependent immune responses, Plays a role in the regulation of antiviral responses, Promotes ubiquitination and proteasomal degradation of MAP3K14, Required for normal antibody isotype switching from IgM to IgG, and plays a central role in the regulation of B-cell survival, and thereby inhibits non-canonical activation of NF-kappa-B, Regulates pathways leading to the activation of NF-kappa-B and MAP kinases |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
CAP-1 CD40bp CRAF1 LAP1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
TRAF3 |
| Short name: |
TRAF3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, tumor necrosis factor receptor-associated factor 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CAP-1 and CAP1 and CD40bp and CRAF1 and IIAE5 and LAP1, Plasma membranes, TRAF3 and IDBG-21240 and ENSG00000131323 and 7187, TRAF3 and IDBG-635183 and ENSBTAG00000013475 and 506182, Traf3 and IDBG-172558 and ENSMUSG00000021277 and 22031, thioesterase binding, this GO :0001817 and regulation of cytokine production and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008063 and Toll signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030162 and regulation of proteolysis and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031996 and thioesterase binding and molecular function this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032648 and regulation of interferon-beta production and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050688 and regulation of defense response to virus and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0004871 : signal transducer activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0019901 : protein kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0031996 : thioesterase binding, this GO :0004871 : signal transducer activity, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0019901 : protein kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0031996 : thioesterase binding, TNF receptor-associated factor 3 |
| Identity: |
12033 |
| Gene: |
TRAF3 |
More about : TRAF3 |
| Long gene name: |
TNF receptor associated factor 3 |
| Locus: |
14q32, 32 |
| Discovery year: |
1998-05-05 |
| GenBank acession: |
U21092 |
| Entrez gene record: |
7187 |
| Pubmed identfication: |
7530216 7859281 |
| RefSeq identity: |
NM_145725 |
| Classification: |
Zinc fingers TNF receptor associated factors |
| Havana BLAST/BLAT: |
OTTHUMG00000171902 |
| Locus Specific Databases: |
LRG_229 |