| Long name: |
DOK4 Primary Polyclonal Antibody |
| Also known as: |
DOK4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DOK4 |
| Specificity: |
This is a highly specific antibody against DOK4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DOK4 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Additionally, Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation, Expressed in a variety of tissues with highest expression in liver, Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, heart, kidney and skeletal muscle, mediate biological responses within the body, suggesting a role for Dok-4 in tumorigenesis, via this interaction, The downstream of kinase family (Dok-1-7) are members of a class of docking proteins that interact with receptor tyrosine kinases and |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DOK4_HUMAN, Downstream of tyrosine kinase 4, FLJ10488, docking protein 4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DOK4 |
| Short name: |
DOK4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DOK4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19868 |
| Gene: |
DOK4 |
More about : DOK4 |
| Long gene name: |
docking protein 4 |
| Synonyms: |
FLJ10488 |
| Locus: |
16q21 |
| Discovery year: |
2002-11-28 |
| GenBank acession: |
BC003541 |
| Entrez gene record: |
55715 |
| Pubmed identfication: |
10493829 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133460 |