| Long name: |
Biotin Conjugated, VGF/NERP1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
VGF/NERP1 |
| Specificity: |
This is a highly specific antibody against VGF/NERP1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NERP1 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Its expression is rapidly induced by injury, Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS), The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, The structural organization of this gene is similar to that of the rat gene, VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line, VGF is widely expressed in both the PNS and CNS, VGF plays an essential role in how the brain regulates energy expenditure and body weight, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene, and is upregulated by nerve growth factor, and neuronal activity, but is especially abundant in the adult hypothalamus, however, its exact function is not known, the circadian clock, This gene is specifically expressed in a subpopulation of neuroendocrine cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
SCG7 SgVII |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
VGF/NERP1 Conjugated |
| Short name: |
Conjugated, VGF/NERP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, VGF/NERP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12684 |
| Gene: |
VGF |
More about : VGF |
| Long gene name: |
VGF nerve growth factor inducible |
| Synonyms name: |
neuro-endocrine specific protein VGF |
| Locus: |
7q22, 1 |
| Discovery year: |
1997-07-22 |
| GenBank acession: |
Y12661 |
| Entrez gene record: |
7425 |
| Pubmed identfication: |
9344675 |
| RefSeq identity: |
NM_003378 |
| Classification: |
Granins |
| Havana BLAST/BLAT: |
OTTHUMG00000157109 |