| Long name: |
VGF/NERP1 Primary Polyclonal Antibody |
| Also known as: |
VGF/NERP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
VGF/NERP1 |
| Specificity: |
This is a highly specific antibody against VGF/NERP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NERP1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Its expression is rapidly induced by injury, Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS), The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, The structural organization of this gene is similar to that of the rat gene, VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line, VGF is widely expressed in both the PNS and CNS, VGF plays an essential role in how the brain regulates energy expenditure and body weight, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene, and is upregulated by nerve growth factor, and neuronal activity, but is especially abundant in the adult hypothalamus, however, its exact function is not known, the circadian clock, This gene is specifically expressed in a subpopulation of neuroendocrine cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Nerve growth factor inducible, Neuroendocrine regulatory peptide-1, Neurosecretory protein VGF, VGF, VGF_HUMAN, NERP-1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
VGF/NERP1 |
| Short name: |
VGF/NERP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
VGF/NERP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12684 |
| Gene: |
VGF |
More about : VGF |
| Long gene name: |
VGF nerve growth factor inducible |
| Synonyms: |
SCG7 SgVII |
| Synonyms name: |
neuro-endocrine specific protein VGF |
| Locus: |
7q22, 1 |
| Discovery year: |
1997-07-22 |
| GenBank acession: |
Y12661 |
| Entrez gene record: |
7425 |
| Pubmed identfication: |
9344675 |
| RefSeq identity: |
NM_003378 |
| Classification: |
Granins |
| Havana BLAST/BLAT: |
OTTHUMG00000157109 |