| Long name: |
SPG21 Primary Polyclonal Antibody |
| Also known as: |
SPG21 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SPG21 |
| Specificity: |
This is a highly specific antibody against SPG21 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPG21 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Belonging to the AB hydrolase superfamily, Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network, The gene encoding Maspardin is encoded by human chromosome 15, an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs, which houses over 700 genes and comprises nearly 3% of the human genome, Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ACP33, BM-019, BM019, GL010, MAST, Maspardin, SPG21 antibody, SPG21_HUMAN, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, Acid cluster protein 33 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SPG21 |
| Short name: |
SPG21 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Mast syndrome) (Antibody to), spastic paraplegia 21 (autosomal recessive |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD4 receptor binding, Mast syndrome), SPG21 and IDBG-16930 and ENSG00000090487 and 51324, SPG21 and IDBG-645311 and ENSBTAG00000011540 and 404069, Spg21 and IDBG-177905 and ENSMUSG00000032388 and 27965, nuclei, this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0008219 and cell death and biological process this GO :0010008 and endosome membrane and cellular component this GO :0030140 and trans- this GO lgi network transport vesicle and cellular component this GO :0042609 and CD4 receptor binding and molecular function this GO :0050851 and antigen receptor-mediated signaling pathway and biological process, this GO :0042609 : CD4 receptor binding, this GO :0042609 : CD4 receptor binding, spastic paraplegia 21 (autosomal recessive |
| Identity: |
20373 |
| Gene: |
SPG21 |
More about : SPG21 |
| Long gene name: |
SPG21, maspardin |
| Synonyms gene name: |
Mast syndrome) , spastic paraplegia 21 (autosomal recessive |
| Synonyms: |
ACP33 GL010 BM-019 MAST |
| Locus: |
15q22, 31 |
| Discovery year: |
2004-04-30 |
| GenBank acession: |
AF208861 |
| Entrez gene record: |
51324 |
| Pubmed identfication: |
11113139 14564668 |
| RefSeq identity: |
NM_016630 |
| Havana BLAST/BLAT: |
OTTHUMG00000133098 |