| Long name: |
ALEXA FLUOR 350 Conjugated, ELAVL2 + ELAVL4 Polyclonal Antibody |
| Also known as: |
Anti-ELAVL2 + ELAVL4 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ELAVL2 + ELAVL4 |
| Specificity: |
This is a highly specific antibody against ELAVL2 + ELAVL4 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
70-120/359 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ELAVL2 |
| Gene ID Number: |
19931996 |
| Swiss Prot: |
P25378, Q12926 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation, An additional mammalian homolog, Characteristically, Elav, Elav proteins function within the nucleus, HuD and Hel-N1, HuR, Several mammalian Elav-like proteins, When Elav-like proteins associate with these ARE sites this degradation is inhibited, a Drosophila protein and the first described member, and they are shuttled between the nucleus and cytoplasm by a nuclear export signal, are also expressed in postmitotic neurons, designated HuC, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance, is ubiquitously expressed and is also overexpressed in a wide variety of tumors, leading to an increased stability of the corresponding transcript, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts, which is a regulatory feature of the Elav-like proteins as it limits their accessibility to ARE sites, which is also designated HuA, The Elav-like genes encode for a family of RNA-binding proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
PNEM |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
ELAVL2 + ELAVL4 |
| Short name: |
ELAVL2 + ELAVL4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, ELAVL2 and ELAVL4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3315 |
| Gene: |
ELAVL4 |
More about : ELAVL4 |
| Long gene name: |
ELAV like RNA binding protein 4 |
| Synonyms gene: |
HUD |
| Synonyms gene name: |
Drosophila)-like 4 (Hu antigen D) ELAV (embryonic lethal, Drosophila)-like 4 ELAV like neuron-specific RNA binding protein 4 , ELAV (embryonic lethal, abnormal vision, abnormal vision |
| Synonyms name: |
Hu antigen D |
| Locus: |
1p33-p32, 3 |
| Discovery year: |
1993-07-12 |
| GenBank acession: |
AY033998 |
| Entrez gene record: |
1996 |
| Pubmed identfication: |
8222755 |
| RefSeq identity: |
NM_021952 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000007877 |