| Long name: |
N-cadherin Primary Polyclonal Antibody |
| Also known as: |
N-cadherin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
N-cadherin |
| Specificity: |
This is a highly specific antibody against N-cadherin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
746-790/906 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human N-cadherin |
| Gene ID number: |
1000 |
| Swiss Prot: |
P19022 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2 may be involved in neuronal recognition mechanism, CDH2-mediated anchorage is affected, In hippocampal neurons, They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types, leading to modulate neural stem cell quiescence, may regulate dendritic spine density (By similarity), Cadherins are calcium-dependent cell adhesion proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD325, CDH2, CDw325, Cadherin-2, N-cadherin, NCAD, Neural cadherin, CDHN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
N-cadherin |
| Short name: |
N-cadherin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
N-cadherin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1759 |
| Gene: |
CDH2 |
More about : CDH2 |
| Long gene name: |
cadherin 2 |
| Synonyms gene: |
NCAD |
| Synonyms gene name: |
N-cadherin (neuronal) , cadherin 2, type 1 |
| Synonyms: |
CDHN CD325 |
| Synonyms name: |
N-cadherin |
| Locus: |
18q12, 1 |
| Discovery year: |
1991-09-13 |
| GenBank acession: |
S42303 |
| Entrez gene record: |
1000 |
| Pubmed identfication: |
2384753 7731968 2216790 |
| RefSeq identity: |
NM_001792 |
| Classification: |
Type I classical cadherins CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000059940 |