| Long name: |
FITC Conjugated, KCNQ2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KCNQ2 |
| Specificity: |
This is a highly specific antibody against KCNQ2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human KCNQ2 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Benign familial neonatal convulsions (BFNC), Both proteins display a broad distribution within the brain, Epilepsy results from an electrical hyperexcitability in the central nervous system, KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains, Potassium channels are important regulators of electrical signaling, an autosomal dominant epilepsy of infancy, determining the firing properties and responsiveness of a variety of neurons, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes, with expression patterns that largely overlap, &euro, &trade, 5% of the worldâ, Epilepsy affects about 0, s population and has a large genetic component |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Kv7, 2 ENB1 BFNC KCNA11 HNSPC |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
KCNQ2 Conjugated |
| Short name: |
FITC Conjugated, KCNQ2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, KCNQ2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6296 |
| Gene: |
KCNQ2 |
More about : KCNQ2 |
| Long gene name: |
potassium voltage-gated channel subfamily Q member 2 |
| Synonyms gene: |
EBN EBN1 |
| Synonyms gene name: |
KQT-like subfamily, member 2 , member 2 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q |
| Locus: |
20q13, 33 |
| Discovery year: |
1998-01-12 |
| GenBank acession: |
AF033348 |
| Entrez gene record: |
3785 |
| Pubmed identfication: |
9425895 16382104 |
| RefSeq identity: |
NM_172109 |
| Classification: |
Potassium voltage-gated channels |
| Havana BLAST/BLAT: |
OTTHUMG00000033049 |