| Long name: |
FITC Conjugated, GALR3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GALR3 |
| Specificity: |
This is a highly specific antibody against GALR3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GALR3 |
| Gene ID number: |
8484 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binding of galanin to galanin receptors results in increased feeding, GALR3 mRNA is highly expressed in the hypothalamus, GALR3 mRNA is widely distributed, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, In human, Like GALR1, Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4, and is expressed to a lesser extent in adrenal gland and pancreas, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, but expressed at low abundance, enhanced opiate analgesia and decreased opiate place preference, impaired learning, pituitary and testis, respectively, the gastrointestinal tract and in the endocrine and exocrine pancreas, the pituitary gland, which are linked to the regulation of neurotransmitter release, which is distributed throughout the central and peripheral nervous system, GALR3 a 368 and 370 amino acid protein in human and rat |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GALR3 Conjugated |
| Short name: |
FITC Conjugated, GALR3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GALR3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4134 |
| Gene: |
GALR3 |
More about : GALR3 |
| Long gene name: |
galanin receptor 3 |
| Locus: |
22q13, 1 |
| Discovery year: |
1998-12-17 |
| GenBank acession: |
AF073799 |
| Entrez gene record: |
8484 |
| Pubmed identfication: |
9722565 9832121 |
| Classification: |
Galanin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000150658 |