| Long name: |
Torsin A Primary Polyclonal Antibody |
| Also known as: |
Torsin A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Torsin A |
| Specificity: |
This is a highly specific antibody against Torsin A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Torsin A |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Early-onset torsion dystonia is a movement disorder, Symptoms are believed to result from altered neuronal communication in the basal ganglia, The gene which encodes TorsinA has high homology to three additional mammalian genes and a nematode gene and distal similarity to the family of heat-shock proteins and the Clp protease family, The gene which encodes TorsinA maps to human chromosome 9q34, The proteins display cytoplasmic distribution, TorsinA comprises 332 amino acids, TorsinA is widely expressed throughout the mouse central nervous system and is detected in the majority of neurons in nearly all regions, TorsinA often performs chaperone-like functions that assist in the assembly, although in some types of neurons localization is perinuclear, characterized by twisting muscle contractures, has been identified as the cause of one form of autosomal dominantly inherited dystonia, operation, or dis-assembly of protein complexes, that begins in childhood, which codes for TorsinA, A mutation of the DYT1 gene |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Dystonia 1, Dystonia 1 protein, Dyt1, TOR1A_HUMAN, Tor1a, Torsin A, Torsin family 1 member A, DQ2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Torsin A |
| Short name: |
Torsin A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Torsin A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11996 |
| Gene: |
TOR2A |
More about : TOR2A |
| Long gene name: |
torsin family 2 member A |
| Synonyms gene name: |
member A , torsin family 2 |
| Synonyms: |
FLJ14771 TORP1 |
| Locus: |
9q34, 11 |
| Discovery year: |
2000-02-17 |
| GenBank acession: |
AA873275 |
| Entrez gene record: |
27433 |
| Pubmed identfication: |
10644435 |
| RefSeq identity: |
NM_130459 |
| Havana BLAST/BLAT: |
OTTHUMG00000020706 |