| Long name: |
FITC Conjugated, NMUR1/GPR66 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NMUR1/GPR66 |
| Specificity: |
This is a highly specific antibody against NMUR1/GPR66 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human NMUR1 |
| Gene ID number: |
10316 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide, It is widely expressed in gastrointestinal systems and central nervous system (CNS), It may also be detected in testis but has low levels of expression in peripheral tissues, Itâ, NMUR1 is detected in peripheral organs, NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins, Peripheral activities of neuromedin U include smooth muscle stimulation, but the protein has been detected in cerebellum, dorsal root ganglia and spinal cord, hippocampus, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function, particularly in urogenital and gastrointestinal systems, spinal cord and thalamus, with highest levels in testis, &euro, &trade, Neuromedin U is a neuropeptide with high activity on smooth muscle, s expression in CNS is low |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
GPC-R FM-3 NMU1R |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NMUR1/GPR66 Conjugated |
| Short name: |
FITC Conjugated, NMUR1/GPR66 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, NMUR1/GPR66 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4518 |
| Gene: |
NMUR1 |
More about : NMUR1 |
| Long gene name: |
neuromedin U receptor 1 |
| Synonyms gene: |
GPR66 |
| Synonyms gene name: |
G protein-coupled receptor 66 |
| Locus: |
2q37, 1 |
| Discovery year: |
1999-06-02 |
| GenBank acession: |
AF044600 |
| Entrez gene record: |
10316 |
| Pubmed identfication: |
9782091 |
| RefSeq identity: |
NM_006056 |
| Classification: |
Neuromedin U receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133225 |