| Long name: |
Synaptotagmin XI Primary Polyclonal Antibody |
| Also known as: |
Synaptotagmin XI PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Synaptotagmin XI |
| Specificity: |
This is a highly specific antibody against Synaptotagmin XI |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Synaptotagmin XI |
| Gene ID number: |
23208 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, Like other Synaptotagmin proteins, Synaptotagmin XI, Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinsonâ, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking, also known as SYT11 (Synaptotagmin-11), including schizophrenia and Parkinsonâ, is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung, the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex, &euro, &euro, &trade, &trade, Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles, s disease, s disease gene product) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DKFZp781D015, KIAA0080, MGC10881, MGC17226, SYT 11, SYT 12, SYT-11, SYT-12, SYT11_HUMAN, SYT12, Synaptotagmin 12, Synaptotagmin XI, Synaptotagmin-11, Synaptotagmin-11, Synaptotagmin-12, Synaptotagmin11, Synaptotagmin12, SynaptotagminXI, Syt XI, Syt11, SytXI, synaptotagmin XII, synaptotagmin-XII, Synaptotagmin 11 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Synaptotagmin XI |
| Short name: |
Synaptotagmin XI Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Synaptotagmin XI (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19239 |
| Gene: |
SYT11 |
More about : SYT11 |
| Long gene name: |
synaptotagmin 11 |
| Synonyms gene name: |
synaptotagmin XI |
| Synonyms: |
KIAA0080 MGC10881 MGC17226 DKFZp781D015 |
| Locus: |
1q22 |
| Discovery year: |
2002-09-20 |
| GenBank acession: |
D38522 |
| Entrez gene record: |
23208 |
| Pubmed identfication: |
11543631 |
| RefSeq identity: |
NM_152280 |
| Classification: |
Synaptotagmins |
| Havana BLAST/BLAT: |
OTTHUMG00000014105 |