| Long name: |
Piccolo Primary Polyclonal Antibody |
| Also known as: |
Piccolo PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Piccolo |
| Specificity: |
This is a highly specific antibody against Piccolo |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Piccolo |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Bassoon, Bassoon is a large protein which is also found in the presynaptic compartments of rat brain synapses, Bassoon is found in axon terminals of hippocampal neurons where it is highly concentrated in the vicinity of the active zone, Bassoon may be involved in cytomatrix organization at the site of neurotransmitter release, Piccolo has a similar distribution and colocalizes with Bassoon in cultured hippocampal cells, Piccolo zinc fingers interact with the dual prenylated rab3A and VAMP2/ Synaptobrevin II receptor PRA, The gene which encodes bassoon maps to human chromosome 3p21, The gene which encodes piccolo maps to human chromosome 7q21, along with Piccolo, is part of the ensemble of presynaptic proteins that are involved in orchestrating events at the nerve terminal, 11, 31, Piccolo is 1 component of the presynaptic cytomatrix |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Aczonin, Brain-derived HLMN protein, DKFZp779G1236, KIAA0559, Multidomain presynaptic cytomatrix protein, PCLO, PCLO_HUMAN, Piccolo, Piccolo presynaptic cytomatrix protein, Presynaptic cytomatrix protein, Protein piccolo, homolog of antibody Pico, mouse, ACZ |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Piccolo |
| Short name: |
Piccolo Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Piccolo (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13406 |
| Gene: |
PCLO |
More about : PCLO |
| Long gene name: |
piccolo presynaptic cytomatrix protein |
| Synonyms gene name: |
piccolo (presynaptic cytomatrix protein) |
| Synonyms: |
KIAA0559 DKFZp779G1236 ACZ |
| Synonyms name: |
aczonin |
| Locus: |
7q21, 11 |
| Discovery year: |
2001-06-25 |
| GenBank acession: |
AB011131 |
| Entrez gene record: |
27445 |
| Pubmed identfication: |
8900486 9628581 |
| RefSeq identity: |
NM_014510 |
| Classification: |
Zinc fingers PDZ domain containing C2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000154853 |