| Long name: |
ALEXA FLUOR 647 Conjugated, MAGI1/IRSP58 Polyclonal Antibody |
| Also known as: |
Anti-MAGI1/IRSP58 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MAGI1/IRSP58 |
| Specificity: |
This is a highly specific antibody against MAGI1/IRSP58 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAGI1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
MAGI-1, MAGI-1a and MAGI-1b, MAGI-1c, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), MAGI-2 and MAGI-3 are localized to the plasma membrane, The closely related MAGUK proteins, The third isoform, The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals, Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, Two variants, and it is primarily expressed in the liver and kidney, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, however, likewise contain the GuK domain and five PDZ domains, the SH3 domain and the guanylate kinase (GuK) domain, the SH3 domain is replaced with a WW domain, The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
FLJ31349 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MAGI1/IRSP58 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MAGI1/IRSP58 |
| Short name: |
MAGI1/IRSP58 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, WW and PDZ domain containing 1/IRSP58 (Antibody to), membrane associated guanylate kinase |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AIP-3 and AIP3 and BAIAP1 and BAP-1 and BAP1 and MAGI-1 and Magi1d and TNRC19 and WWP3, MAGI1 and IDBG-43316 and ENSG00000151276 and 9223, MAGI1 and IDBG-645100 and ENSBTAG00000010581 and 783484, Magi1 and IDBG-171358 and ENSMUSG00000045095 and 14924, WW and PDZ domain containing 1, alpha-actinin binding, nuclei, this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0042995 and cell projection and cellular component this GO :0051393 and alpha-actinin binding and molecular function this GO :0070997 and neuron death and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008022 : protein C-terminus binding and also this GO :0051393 : alpha-actinin binding, this GO :0005524 : ATP binding, this GO :0008022 : protein C-terminus binding, this GO :0051393 : alpha-actinin binding, membrane associated guanylate kinase |
| Identity: |
23034 |
| Gene: |
CNKSR3 |
More about : CNKSR3 |
| Long gene name: |
CNKSR family member 3 |
| Synonyms gene: |
MAGI1 |
| Synonyms gene name: |
membrane associated guanylate kinase interacting protein-like 1 |
| Locus: |
6q25, 2 |
| Discovery year: |
2003-11-26 |
| GenBank acession: |
AK055911 |
| Entrez gene record: |
154043 |
| RefSeq identity: |
NM_173515 |
| Classification: |
Sterile alpha motif domain containing PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015873 |