| Long name: |
Cy7 Conjugated, C1QC/C1QG Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
C1QC/C1QG |
| Specificity: |
This is a highly specific antibody against C1QC/C1QG |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human C1QC |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
C1q-B and C1q-C cause inactivation of the classical pathway, Defects in C1q-A, However, Macrophages are the primary source of C1q, Six of these subunits are disulfide-linked dimers of chains A and B, The presence of receptors for C1q on effector cells modulates its activity, a subcomponent of the classical complement pathway, and perhaps thrombotic complications resulting from immune injury, are disulfide-linked dimers of chain C, as well as the protein, designated C1q-A through C1q-C, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response, its ability to modulate the interaction of platelets with collagen and immune complexes suggests C1q influences homeostasis as well as other immune activities, leading to a rare genetic disorder characterized by lupus-like symptoms, which may be antibody-dependent or independent, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA, while three of these subunits, C1q |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
C1QC/C1QG Conjugated |
| Short name: |
Conjugated, C1QC/C1QG Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
C chain/C1QG (Antibody to), cyanine 7 coupled, q subcomponent, complement component 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C chain, C1Q-C and C1QG, C1QC and IDBG-645502 and ENSBTAG00000011193 and 509968, C1QC and IDBG-93737 and ENSG00000159189 and 714, C1qc and IDBG-198256 and ENSMUSG00000036896 and 12262, Extracellular, classical pathway and biological process this GO :0030853 and negative regulation of granulocyte differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0045650 and negative regulation of macrophage differentiation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072562 and blood microparticle and cellular component, protein binding, q subcomponent, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006955 and immune response and biological process this GO :0006956 and complement activation and biological process this GO :0006958 and complement activation, this GO :0005515 : protein binding, this GO :0005515 : protein binding, complement component 1 |
| Identity: |
1245 |
| Gene: |
C1QC |
More about : C1QC |
| Long gene name: |
complement C1q C chain |
| Synonyms gene: |
C1QG |
| Synonyms gene name: |
C chain , complement component 1, gamma polypeptide complement component 1, q subcomponent, q subcomponent |
| Locus: |
1p36, 12 |
| Discovery year: |
1991-09-12 |
| GenBank acession: |
AK057792 |
| Entrez gene record: |
714 |
| Pubmed identfication: |
1706597 |
| RefSeq identity: |
NM_172369 |
| Classification: |
Complement system |
| Havana BLAST/BLAT: |
OTTHUMG00000002891 |
| Locus Specific Databases: |
C1QCbase: Mutation registry for C1qC deficiency LRG_24 |