| Long name: |
FITC Conjugated, APBA1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APBA1 |
| Specificity: |
This is a highly specific antibody against APBA1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human APBA1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
(also designated Mint 1), Multiple splice varitents of X11 have been identified, The Beta-Amyloid precursor is known to interact with several proteins, The neuronal, X11 binds specifically to the YENPTY motif, X11Beta (Mint 2) and X11(Mint 3), including X11 and the G heterotrimetric protein APP-BP1, including X11&, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways, transmembrane protein X11 is known to bind to the â, which is involved in the internalization of Beta-APP, &circ, &euro, «, &trade, -Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimerâ, aring, s disease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
D9S411E X11 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APBA1 Conjugated |
| Short name: |
FITC Conjugated, APBA1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
family A, fluorecein coupled, member 1 (Antibody to), amyloid b (A4) precursor protein-binding |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
APBA1 and IDBG-631959 and ENSBTAG00000008877 and 515571, APBA1 and IDBG-69588 and ENSG00000107282 and 320, Apba1 and IDBG-154300 and ENSMUSG00000024897 and 319924, D9S411E and LIN10 and MINT1 and X11 and X11A and X11ALPHA, family A, member 1, nuclei, phosphatidylinositol-4, this GO :0001540 and beta-amyloid binding and molecular function this GO :0001701 and in utero embryonic development and biological process this GO :0005515 and protein binding and molecular function this GO :0005546 and phosphatidylinositol-4, this GO :0001540 : beta-amyloid binding, this GO :0001540 : beta-amyloid binding and also this GO :0005515 : protein binding and also this GO :0005546 : phosphatidylinositol-4, this GO :0005515 : protein binding, this GO :0005546 : phosphatidylinositol-4, this GO :0030165 : PDZ domain binding, this GO :0032403 : protein complex binding, 5-bisphosphate binding, 5-bisphosphate binding and also this GO :0030165 : PDZ domain binding and also this GO :0032403 : protein complex binding, 5-bisphosphate binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0007155 and cell adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007399 and nervous system development and biological process this GO :0007626 and locomotory behavior and biological process this GO :0008021 and synaptic vesicle and cellular component this GO :0008088 and axon car this GO transport and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0014047 and glutamate secretion and biological process this GO :0014051 and gamma-aminobutyric acid secretion and biological process this GO :0016020 and membrane and cellular component this GO :0030165 and PDZ domain binding and molecular function this GO :0032403 and protein complex binding and molecular function this GO :0035264 and multicellular organism growth and biological process this GO :0043234 and protein complex and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component, amyloid beta (A4) precursor protein-binding |
| Identity: |
578 |
| Gene: |
APBA1 |
More about : APBA1 |
| Long gene name: |
amyloid beta precursor protein binding family A member 1 |
| Synonyms gene: |
MINT1 |
| Synonyms gene name: |
amyloid beta (A4) precursor protein-binding, family A, member 1 |
| Locus: |
9q21, 12 |
| Discovery year: |
1997-06-25 |
| GenBank acession: |
AF029106 |
| Entrez gene record: |
320 |
| Pubmed identfication: |
7678331 7719031 |
| RefSeq identity: |
NM_001163 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019984 |