| Long name: |
ALEXA FLUOR 488 Conjugated, APBA1 Polyclonal Antibody |
| Also known as: |
Anti-APBA1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APBA1 |
| Specificity: |
This is a highly specific antibody against APBA1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APBA1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
(also designated Mint 1), Multiple splice varitents of X11 have been identified, The Beta-Amyloid precursor is known to interact with several proteins, The neuronal, X11 binds specifically to the YENPTY motif, X11Beta (Mint 2) and X11(Mint 3), including X11 and the G heterotrimetric protein APP-BP1, including X11&, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways, transmembrane protein X11 is known to bind to the â, which is involved in the internalization of Beta-APP, &circ, &euro, «, &trade, -Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimerâ, aring, s disease |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
D9S411E X11 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the APBA1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
APBA1 |
| Short name: |
APBA1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, family A, member 1 (Antibody to), amyloid b (A4) precursor protein-binding |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
APBA1 and IDBG-631959 and ENSBTAG00000008877 and 515571, APBA1 and IDBG-69588 and ENSG00000107282 and 320, Apba1 and IDBG-154300 and ENSMUSG00000024897 and 319924, D9S411E and LIN10 and MINT1 and X11 and X11A and X11ALPHA, family A, member 1, nuclei, phosphatidylinositol-4, this GO :0001540 and beta-amyloid binding and molecular function this GO :0001701 and in utero embryonic development and biological process this GO :0005515 and protein binding and molecular function this GO :0005546 and phosphatidylinositol-4, this GO :0001540 : beta-amyloid binding, this GO :0001540 : beta-amyloid binding and also this GO :0005515 : protein binding and also this GO :0005546 : phosphatidylinositol-4, this GO :0005515 : protein binding, this GO :0005546 : phosphatidylinositol-4, this GO :0030165 : PDZ domain binding, this GO :0032403 : protein complex binding, 5-bisphosphate binding, 5-bisphosphate binding and also this GO :0030165 : PDZ domain binding and also this GO :0032403 : protein complex binding, 5-bisphosphate binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0007155 and cell adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007399 and nervous system development and biological process this GO :0007626 and locomotory behavior and biological process this GO :0008021 and synaptic vesicle and cellular component this GO :0008088 and axon car this GO transport and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0014047 and glutamate secretion and biological process this GO :0014051 and gamma-aminobutyric acid secretion and biological process this GO :0016020 and membrane and cellular component this GO :0030165 and PDZ domain binding and molecular function this GO :0032403 and protein complex binding and molecular function this GO :0035264 and multicellular organism growth and biological process this GO :0043234 and protein complex and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component, amyloid beta (A4) precursor protein-binding |
| Identity: |
578 |
| Gene: |
APBA1 |
More about : APBA1 |
| Long gene name: |
amyloid beta precursor protein binding family A member 1 |
| Synonyms gene: |
MINT1 |
| Synonyms gene name: |
amyloid beta (A4) precursor protein-binding, family A, member 1 |
| Locus: |
9q21, 12 |
| Discovery year: |
1997-06-25 |
| GenBank acession: |
AF029106 |
| Entrez gene record: |
320 |
| Pubmed identfication: |
7678331 7719031 |
| RefSeq identity: |
NM_001163 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019984 |