| Long name: |
ALEXA FLUOR 594 Conjugated, C1QBP/GC1q R Polyclonal Antibody |
| Also known as: |
Anti-C1QBP/GC1q R PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
C1QBP/GC1q R |
| Specificity: |
This is a highly specific antibody against C1QBP/GC1q R |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C1QBP |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
C1QBP has been described as a complement receptor for C1q on B cells, C1QBP is a subunit of pre-mRNA splicing factor SF2/ASF, C1QBP is expressed in vascular endothelial cells and has been found to be a multifunctional protein interacting with elements of complement, C1q binding protein (C1QBP), In addition, The C1QBP protein may form homodimers, The SCS contains over 30 glycoproteins that influence physiological mechanisms of the body in response to immune complex (the classical pathway), also designated gC1q-R, carbohydrate (the lectin pathway) or bacterial (alternative pathway) initiation, coagulation and kinin systems, is known to bind the globular heads of C1q molecules and inhibit C1 activation, neutrophils and mast cells, p32 (p33) or HABP1 (hyaluronan-binding protein 1), The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system (SCS) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
gC1Q-R gC1qR p32 SF2p32 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
C1QBP/GC1q R |
| Short name: |
C1QBP/GC1q R Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, q subcomponent binding protein/GC1q R (Antibody to), complement component 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C1QBP and IDBG-21497 and ENSG00000108561 and 708, C1QBP and IDBG-634029 and ENSBTAG00000012739 and 518321, C1qbp and IDBG-195770 and ENSMUSG00000018446 and 12261, DNA-templated and biological process this GO :0006397 and mRNA processing and biological process this GO :0006915 and apoptotic process and biological process this GO :0006955 and immune response and biological process this GO :0006958 and complement activation, classical pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0007597 and blood coagulation, gC1Q-R and GC1QBP and gC1qR and HABP1 and p32 and SF2p32, intrinsic pathway and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008380 and RNA splicing and biological process this GO :0009986 and cell surface and cellular component this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0030984 and kininogen binding and molecular function this GO :0031690 and adrenergic receptor binding and molecular function this GO :0032689 and negative regulation of interferon-gamma production and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0039534 and negative regulation of MDA-5 signaling pathway and biological process this GO :0039536 and negative regulation of RIG-I signaling pathway and biological process this GO :0042256 and mature ribosome assembly and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0048025 and negative regulation of mRNA splicing, mitochondrial ribosome binding, nuclei, q subcomponent binding protein, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001849 and complement component C1q binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0003729 and mRNA binding and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005540 and hyaluronic acid binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0001849 : complement component C1q binding, this GO :0001849 : complement component C1q binding and also this GO :0003714 : transcription corepressor activity and also this GO :0003729 : mRNA binding and also this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0005540 : hyaluronic acid binding and also this GO :0008134 : transcription factor binding and also this GO :0030984 : kininogen binding and also this GO :0031690 : adrenergic receptor binding and also this GO :0097177 : mitochondrial ribosome binding, this GO :0003714 : transcription corepressor activity, this GO :0003729 : mRNA binding, this GO :0005080 : protein kinase C binding, this GO :0005515 : protein binding, this GO :0005540 : hyaluronic acid binding, this GO :0008134 : transcription factor binding, this GO :0030984 : kininogen binding, this GO :0031690 : adrenergic receptor binding, this GO :0097177 : mitochondrial ribosome binding, via spliceosome and biological process this GO :0050687 and negative regulation of defense response to virus and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0070131 and positive regulation of mitochondrial translation and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process this GO :0097177 and mitochondrial ribosome binding and molecular function this GO :1900026 and positive regulation of substrate adhesion-dependent cell spreading and biological process this GO :1901165 and positive regulation of trophoblast cell migration and biological process this GO :2000510 and positive regulation of dendritic cell chemotaxis and biological process, complement component 1 |
| Identity: |
1243 |
| Gene: |
C1QBP |
More about : C1QBP |
| Long gene name: |
complement C1q binding protein |
| Synonyms gene: |
HABP1 |
| Synonyms gene name: |
complement component 1, q subcomponent binding protein |
| Synonyms name: |
C1q globular domain-binding protein hyaluronan-binding protein 1 splicing factor SF2-associated protein |
| Locus: |
17p13, 2 |
| Discovery year: |
1995-12-11 |
| GenBank acession: |
X75913 |
| Entrez gene record: |
708 |
| Pubmed identfication: |
8567680 8195709 |
| RefSeq identity: |
NM_001212 |
| Havana BLAST/BLAT: |
OTTHUMG00000177875 |