| Long name: |
ATRIP (Ser68+Ser72) Primary Polyclonal Antibody |
| Also known as: |
ATRIP (Ser68+Ser72) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ATRIP Ser68+Ser72 |
| Specificity: |
This is a highly specific antibody against ATRIP Ser68+Ser72 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser68+Ser72 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ATRIP around the phosphorylation site of Ser68 + Ser72 [LA(p-S)QAL(p-S)QC] |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ATM and ATR kinases are important for cell cycle checkpoint response signalling, ATR-interacting protein (ATRIP), ATRIP is a nuclear protein that may also play a role in protein stabilization, ATRIP is a ubiquitously expressed protein that can form heterodimers with ATR, After dimerization they bind the RPA complex and are recruited to single stranded DNA, Checkpoint proteins include Rad17, Chk2, In response to DNA damage, It is also important for ATR expression, Rad1, Rad9 and Hus1, also designated ATM and Rad3-related-interacting protein, is required for checkpoint signaling after DNA damage, which are involved in regulating cell cycle arrest at the G2 checkpoint, which is involved in regulating cell cycle progression at the G1 checkpoint as well as Chk1, which regulates DNA replication and damage checkpoint responses, DNA damage or incomplete replication of DNA results in the inhibition of cell cycle progression at the G1 to S or the G2 to M phase transition by conserved regulatory mechanisms known as cell cycle checkpoints |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
3' repair exonuclease 1, 3'-5' exonuclease TREX1, AGS 1, AGS-1, AGS1, ATIP, ATM and Rad3 related interacting protein, ATM and Rad3-related-interacting protein, ATR interacting protein, ATR-interacting protein, ATRIP Ser68 + Ser72, ATRIP_HUMAN, Aicardi Goutieres syndrome 1, Atrip, DKFZp434J0310, DKFZp762J2115, DNase III, DRN 3, DRN3, Deoxyribonuclease III dnaQ/mutD E, FLJ12343, MGC20625, MGC21482, MGC26740, P-ATRIP Ser68/Ser72, TREX 1, TREX1, TREX1 protein, Three prime repair exonuclease 1, coli like, ATRIP phospho S68 + S72 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ATRIP (Ser68+Ser72) |
| Short name: |
ATRIP (Ser68+Ser72) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ATRIP (Ser68+Ser72) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
33499 |
| Gene: |
ATRIP |
More about : ATRIP |
| Long gene name: |
ATR interacting protein |
| Synonyms: |
FLJ12343 MGC20625 MGC21482 MGC26740 |
| Locus: |
3p21, 31 |
| Discovery year: |
2007-06-20 |
| GenBank acession: |
AF451323 |
| Entrez gene record: |
84126 |
| Pubmed identfication: |
11721054 |
| RefSeq identity: |
NM_130384 |
| Havana BLAST/BLAT: |
OTTHUMG00000133532 |