| Long name: |
FITC Conjugated, TMPRSS5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TMPRSS5 |
| Specificity: |
This is a highly specific antibody against TMPRSS5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TMPRSS5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A member of the peptidase S1 family, Defects in the gene encoding TMPRSS5 are associated with deafness, TMPRSS5 (transmembrane protease, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, allow desquamation of tumor cells into the surrounding environment, also known as spinesin, and is encoded by a gene that maps to human chromosome 11q23, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors, serine 5), 2, Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MGC141886 MGC148044 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TMPRSS5 Conjugated |
| Short name: |
FITC Conjugated, TMPRSS5 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TMPRSS5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14908 |
| Gene: |
TMPRSS5 |
More about : TMPRSS5 |
| Long gene name: |
serine 5 , transmembrane protease |
| Synonyms name: |
spinesin |
| Locus: |
11q23, 2 |
| Discovery year: |
2001-04-05 |
| GenBank acession: |
AB028140 |
| Entrez gene record: |
80975 |
| RefSeq identity: |
NM_030770 |
| Classification: |
Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000168186 |