| Long name: |
FITC Conjugated, DOK6 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DOK6 |
| Specificity: |
This is a highly specific antibody against DOK6 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DOK6 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK), Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1, Dok-5 transcript is abundant in muscle and increases during T cell activation, Dok-6 is highly expressed in the developing central nervous system, It associates with Ret to transduce Ret-mediated processes such as axonal projection, and may constitute a subfamily of the DOK genes, which contain multiple tyrosine residues and putative SH2 binding sites, &euro, &euro, &oelig, The downstream of kinase family (Dok-1-7) are members of a class of â, dockingâ, proteins that include the tyrosine kinase substrates IRS-1 and Cas |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MGC20785 HsT3226 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DOK6 Conjugated |
| Short name: |
FITC Conjugated, DOK6 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DOK6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28301 |
| Gene: |
DOK6 |
More about : DOK6 |
| Long gene name: |
docking protein 6 |
| Synonyms gene: |
DOK5L |
| Synonyms gene name: |
docking protein 5-like |
| Locus: |
18q22, 2 |
| Discovery year: |
2004-05-05 |
| GenBank acession: |
AK057795 |
| Entrez gene record: |
220164 |
| Pubmed identfication: |
15286081 |
| RefSeq identity: |
NM_152721 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000178688 |