| Long name: |
MCP1 Primary Polyclonal Antibody |
| Also known as: |
MCP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MCP1 |
| Specificity: |
This is a highly specific antibody against MCP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
95-145/148 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from rat MCP-1 |
| Gene ID number: |
24770 |
| Swiss Prot: |
P14844 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Rat, Mouse |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Augments monocyte anti-tumor activity, Binds to CCR2 and CCR4, Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant, Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family, Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans, May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis, Monomer or homodimer, Processing at the N-terminus can regulate receptor and targetcell selectivity, The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, in equilibrium, it can induce to have relation with inflammation with the immunity various genes turn to record, like psoriasis, rheumatoid arthritis or atherosclerosis, Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils, The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C-C motif chemokine 2, Ccl2, Immediate-early serum-responsive protein JE, Je, Mcp1, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, Scya2, Sigje, Small-inducible cytokine A2, MCP-1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MCP1 |
| Short name: |
MCP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MCP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10618 |
| Gene: |
CCL2 |
More about : CCL2 |
| Long gene name: |
C-C motif chemokine ligand 2 |
| Synonyms gene: |
SCYA2 |
| Synonyms gene name: |
homologous to mouse Sig-je) chemokine (C-C motif) ligand 2 , small inducible cytokine A2 (monocyte chemotactic protein 1 |
| Synonyms: |
MCP1 MCP-1 MCAF SMC-CF GDCF-2 HC11 MGC9434 |
| Synonyms name: |
homologous to mouse Sig-je monocyte chemoattractant protein-1 monocyte chemotactic and activating factor monocyte secretory protein JE small inducible cytokine subfamily A (Cys-Cys), member 2 , monocyte chemotactic protein 1 |
| Locus: |
17q12 |
| Discovery year: |
1990-07-05 |
| GenBank acession: |
BC009716 |
| Entrez gene record: |
6347 |
| Pubmed identfication: |
2004761 |
| RefSeq identity: |
NM_002982 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000132887 |