| Long name: |
Biotin Conjugated, IL-12 beta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IL-12 beta |
| Specificity: |
This is a highly specific antibody against IL-12 beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
220-255/328 |
| Subcellular location: |
Secreted |
| Gene ID number: |
3593 |
| Swiss Prot: |
P29460 |
| Tested applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Associates with IL23A to form the IL-23 interleukin, IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis, IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues, a heterodimeric cytokine which functions in innate and adaptive immunity, activates the Jak-Stat signaling cascade, and stimulate the production of IFN-gamma by resting PBMC, enhance the lytic activity of NK/lymphokine-activated killer cells, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines, Cytokine that can act as a growth factor for activated T and NK cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CLMF p40, CLMF2, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, IL-12B, IL12B, IMD28, IMD29, Interleukin-12 subunit beta, NK cell stimulatory factor chain 2, NKSF, NKSF2, CLMF |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IL-12 beta Conjugated |
| Short name: |
Conjugated, IL-12 beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Interleukin-12 b (Antibody to) |
| Alternative technique: |
antibodies |