| Long name: |
FITC Conjugated, CACNA1B (N type) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CACNA1B N type |
| Specificity: |
This is a highly specific antibody against CACNA1B N type |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
115-132/2339 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human CACNA1B (N type) |
| Gene ID number: |
774 |
| Swiss Prot: |
Q00975 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons, N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA), The isoform alpha-1B gives rise to N-type calcium currents, They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA), cell division and cell death, cell motility, gene expression, hormone or neurotransmitter release, including muscle contraction, Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Cav2, 2 CACNN |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CACNA1B (N Conjugated |
| Short name: |
FITC Conjugated, CACNA1B (N type) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CACNA1B (N classification) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1389 |
| Gene: |
CACNA1B |
More about : CACNA1B |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 B |
| Synonyms gene: |
CACNL1A5 |
| Synonyms gene name: |
N type, alpha 1B subunit , calcium channel, voltage-dependent |
| Locus: |
9q34, 3 |
| Discovery year: |
1995-06-01 |
| GenBank acession: |
AB209467 |
| Entrez gene record: |
774 |
| Pubmed identfication: |
8825650 16382099 |
| RefSeq identity: |
NM_000718 |
| Classification: |
Calcium voltage-gated channel subunits EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000021002 |